Analysis of Liquid CO2 Extract of Hemp Flower and Other Products by GCMS and HPLC

Location

Village Square

Start Date

28-4-2023 11:20 AM

Department

Engineering

Abstract

The cannabis industry uses supercritical carbon dioxide (scCO 2 ) to extract terpenes and cannabinoids for use in concentrated product such as hash rosin and edibles. The benefit to using scCO 2 as opposed to other solvents such as butane—also commonly found in industry extraction—is that CO 2 easily vaporizes out of the final product, eliminating risk of solvent residue in what goes to market. In contrast to scCO 2 , liquid CO 2 extraction is conducted at a lower temperature, which may prevent decarboxylation of THC-A and CBD-A. Also, equipment for scCO 2 extraction is very expensive, while the melloeX liquid CO 2 extraction system provides an affordable laboratory scale for this procedure. As part of our long-term effort to develop undergraduate experiments in cannabis analysis, we analyzed liquid CO 2 extracts of hemp flower and other products by GC-MS and HPLC. We compare these results to extracts using ethanol, dichloromethane, and hexane conducted previously.

Faculty Sponsor

Charles Abrams, Harry S. Truman College

This document is currently not available here.

Share

COinS
 
Apr 28th, 11:20 AM

Analysis of Liquid CO2 Extract of Hemp Flower and Other Products by GCMS and HPLC

Village Square

The cannabis industry uses supercritical carbon dioxide (scCO 2 ) to extract terpenes and cannabinoids for use in concentrated product such as hash rosin and edibles. The benefit to using scCO 2 as opposed to other solvents such as butane—also commonly found in industry extraction—is that CO 2 easily vaporizes out of the final product, eliminating risk of solvent residue in what goes to market. In contrast to scCO 2 , liquid CO 2 extraction is conducted at a lower temperature, which may prevent decarboxylation of THC-A and CBD-A. Also, equipment for scCO 2 extraction is very expensive, while the melloeX liquid CO 2 extraction system provides an affordable laboratory scale for this procedure. As part of our long-term effort to develop undergraduate experiments in cannabis analysis, we analyzed liquid CO 2 extracts of hemp flower and other products by GC-MS and HPLC. We compare these results to extracts using ethanol, dichloromethane, and hexane conducted previously.